ABSTRACT
Governments and companies in all affected countries have taken measures to prevent, on the one hand, the rapid spread of the virus among the population and, on the other hand, to alleviate the economic and commercial consequences of the crisis that is already changing the daily functioning of the population and the companies. The COVID-19 pandemic has radically and unexpectedly transformed the global economic landscape. The objective of this work is to demonstrate a set of information that can meet the expectations of the internal and external stakeholders of an organization concerned with constructively relating to its stakeholders–aiming at the possibility of carrying out the work and serving customers in the context of the pandemic. The research method is the study based on the literature review process focusing on information and research systems, books, and a manufacturer's case study. It also has practical data–information collected from audits carried out. Stakeholders' expectations and interests are connected to this issue and can be aligned through an Audit of Contagion and Transmission Protocols of SARS-COV-2. Copyright © 2021 Muncinelli, Pinheiro de Lima, Vecchia, Moro, Deschamps, Gouvea da Costa and Cestari.
ABSTRACT
Introduction: Laboratories are inextricably dangerous work environ-ments, as fatal incidents are reported in both academic and non-aca-demic environments worldwide, where poor safety culture has been rec-ognized as the major accident contributor. Workers can be exposed to chemical, biological, physical, or radioactive hazards, in addition to mus-culoskeletal stresses. In Brazil, hundreds of thousands of workers are employed in laboratories, either in private or public institutions. Alt-hough laboratory safety can be governed by local, state, or federal regu-lations, learning how to identify common laboratory hazards is the first step to preventing accidents in the lab environment. Methods: The study aimed to assess the degree level of safety culture in an academic population of research laboratories, located in the largest city in Brazil, and their compliance with occupational safety regulations during the COVID-19 outbreak. This study was carried out between Oc-tober and November 2020. The results were obtained from the standard-ized questionnaire used to assess 98 researchers working in laboratories during the COVID-19 pandemic. Results: The majority of respondents (95%) reported being exposed to more than two risks, simultaneously. About two-thirds (66%) of them were not fully aware of the laboratory's risk map. About half of the re-searchers (50%) were lacking in safety culture, and 57%and 43% were preoccupied with chemical and non-chemical hazards, respectively. Per-sonal protective equipment (PPE) during laboratory work was used by most researchers, but 75% of researchers claim that security awareness learning should be a high priority for admission to laboratories. About 39% of researchers agreed that awareness of security must be improved in their laboratories Conclusion: The survey proves the lack of information and attitudes about chemical safety, especially among less experienced researchers, even if they use personal protective equipment when necessary. © 2023 by Animal Bioscience.
ABSTRACT
This research was developed before the world society was taken by surprise by the coronavirus pandemic (COVID-19). This fact accelerated the need for most companies to adapt to the home office regime of their workforce. The trail that the coronavirus has left is one of caution in the labor market and changes in the relationships between employers and employees. The objective of this article is to identify in the literature an overview of the evolution and trends of flexible work arrangements in companies and organizations over time. Data collection from integrative literature review in the Scopus and Web Of Science databases, of articles published without time restriction. The sample consisted of 562 studies, categorized and separated into periods in a longitudinal fashion. The issues that are trending about the future of work were identified, such as flexible work arrangements, the lack of labor legislation on remote work, telecommuting as a tool for sustainability, and the impact of these new work arrangements on work-life balance. In addition, we also have the issues that impact the management of people in telecommuting. We did not search for theses and dissertations that address the theme, which could bring even more recent results, but were beyond the scope of this research methodology. In the face of the coronavirus pandemic, which has taken the world by surprise, there is an impact on traditional work. Companies had to implement remote work urgently, without planning and theoretical foundation. This study is an input for companies and leaders who are dealing with the adoption of flexible working arrangements. In the current pandemic moment, remote work has gained unimaginable proportions. Labor relations need to be adapted and the management of this new modality becomes an urgent need and still under construction for use by business leaders.
ABSTRACT
Background Fulminant myocarditis can cause biventricular dysfunction with a mortality rate over 40%. We report a case with severe biventricular failure due to fulminant myocarditis that was successfully supported by left and right ventricular assist devices. Case A 65-year-old woman presented with chest pain, abdominal pain and diarrhea. She was hypotensive and labs revealed elevated troponin-T of 13.5 ng/mL and lactate of 4.3 mmol/L. She was positive for COVID by antigen testing. She was started on multiple vasopressor infusions and admitted to the intensive care unit. Echocardiogram revealed a severely reduced left ventricular ejection fraction of 15% and severe global hypokinesis. The following day, she developed a wide complex tachycardia that was refractory to amiodarone, lidocaine and multiple defibrillation attempts. She was transferred emergently to the cardiac cath lab where coronary angiography revealed an isolated 70% stenosis of the distal left circumflex artery. A Swan-Ganz catheter was placed that yielded a cardiac index by Fick of 1.2 L/min/m2, systemic vascular resistance of 1270 dynesseccm-5 and mixed venous oxygen saturation of 35%. Decision was made to emergently insert an Impella CP device. That evening, she developed complete heart block and transvenous pacing wire was inserted. Due to frequent suction alarms, decision was made to insert ProtekDuo device, which resulted in hemodynamic stabilization. A temporary coronary sinus pacing lead for atrial capture was inserted to improve atrioventricular synchrony. After several days of monitoring, repeat echocardiogram showed complete recovery of biventricular function and Impella CP and ProtekDuo devices were removed. Decision-making The decision of early implantation of ProtekDuo device was made to provide adequate blood flow to the left ventricular assist device for hemodynamic support. In addition, increased atrioventricular synchrony via insertion of temporary coronary sinus pacing wire improved cardiac output. Conclusion Fulminant myocarditis involving biventricular dysfunction can be supported by the use of simultaneous left and right ventricular assist devices.Copyright © 2023 American College of Cardiology Foundation
ABSTRACT
Due to the COVID-19 pandemic, in March 2020, the Spanish Government announced a total lockdown of the population and the interruption of all nonessential economic activity. From this point, televisions adapted their programming schedules by reducing their usual informative content, such as sport or economic segments. In this context, it would be reasonable to assume that the overall television coverage devoted to the main Spanish brands would decrease, but what about those considered to be most active in the field of corporate social responsibility (CSR)? In this work, we analyze the presence of the Spanish brands that are most valued for their CSR on the four main television channels with the highest audience over the two months of total lockdown, and also in the online press. The study confirms that the television coverage of these brands was not only reduced but was also mostly positive during the pandemic, so it reveals the CSR importance in crisis periods. © The Author(s) 2022.
ABSTRACT
Despite the importance of mental health matters for people's well-being and the essential role of television to help spread medical issues, our study shows that the media coverage of this subject has been poor and somehow trivial during the so-called "pandemic fatigue" in Spain. This research focuses on the 24-hour television broadcast of five channels throughout 16 months, coding the content to identify trends and to know how media covered men-tal health topics all along seven days in January 2021. The analysis reveals a trivial representation of the topic, in-cluding irrelevant references to mental health that may not help make visible problems such as depression, anxiety, or stress. Instead, there seems to be a lack of rigorous analysis of the mental health conditions arising after the pan-demic. We can infer that private broad-casters have a more suitable approach when presenting data, describing people involved or taking advice from mental health professionals. Effective information on mental health requires deep messaging and medical recom-mendations or statements, but from this research, it turns out that there is a touch of frivolity in the way television approaches mental health issues.
ABSTRACT
Distributed teams are a reality for several companies nowadays, many authors covered their benefits and problems, and the rate of adoption of such team's structure by companies is growing fast. Since these teams are more present in companies, a performance measurement system must get adapted to fulfill the gap of not having a vast theory about the subject. To fill that gap, this paper brings results from previous steps in the research (Systematic Literature Review and Qualitative analysis of the data). It presents to a group of experts to reach a consensus on which capabilities are essential to managing/developing distributed teams' performance. The experts were exposed to the information following a Delphi Panel format and provided output that reached consensus and refined the list. The experts indicated that a group of six capabilities (engagement, development of a culture of performance measurement, organizational learning, alignment between planning and execution, accurate information and consistency) are essential to have their performance measurement system working correctly and reaching all functions. The work also identified the success factors for virtual teams, providing directions for the adoption and the monitoring of this kind of team that gained importance during the COVID-19 pandemic.
ABSTRACT
This work aims to present the elements related to production and logistics that companies have used in the last four years and that can lead managers to a correct decision in times of uncertainty based on the literature review. During the pandemic caused by COVID-19, industrial companies in the automotive sector had to adapt to the sharp drop in demand, varying negatively by up to 40% from March to November 2020. As of December 2020, demand increased again, recovering the fall from the pandemic's beginning. Thus, a supply chain did not have enough time to recover and meet that speed. Even with international air freight, there is still a halt in automaker's production lines in the automotive sector. Illustrating that context, we studied a case in a company that operates in Brazil, which produces automotive components for a manufacturer of heavy cargo and passenger vehicles. The company was impacted by the COVID-19 pandemic due to its low level, heightened by its suppliers' delays. The results indicated the need for the company to be prepared for the increase in costs and the search for strategies that minimize the negative impacts still caused by the pandemic context. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.
ABSTRACT
Introduction: Recently, several antidepressants, mood stabilizers, and antipsychotics have been suggested to have favorable effects in the treatment of COVID-19. Objective(s): The aim of this systematic review was to collect evidence from preclinical and clinical studies concerning the scientific evidence for the repurposing of psychotropic drugs in COVID-19 treatment. Method(s): Two independent authors searched PubMed-MEDLINE, Scopus, PsycInfo, Clinical Trial Registration Site US (ClinicalTrials. gov) databases, and reviewed the reference lists of articles for eligible articles published up to May 31st, 2021. All preclinical and clinical studies on the effect of any psychotropic drug on Sars-CoV-2 or patients with COVID-19 were included. The Newcastle-Ottawa scale was used for the quality assessment of clinical studies. This systematic review adheres to the PRISMA guidelines. Result(s): 22 studies were included in the synthesis: 9 clinical studies, 9 preclinical studies, and 4 computational studies. The use of antidepressants, both SSRI and non-SSRI, was associated with a reduced risk of severe complications of COVID-19. Several antipsychotics showed an increased risk for both Sars-CoV-2 infection and severe complications during COVID-19. Conclusion(s): The current evidence supports a potential anti- SARS-CoV-2 role for several antidepressants, while the evidence on mood stabilizers or antipsychotics remains controversial. Drug repurposing proved highly successful in response to the current pandemic and psychotropic medications are widely used in clinical practice with well-known safety and tolerability profiles, showing antiviral, immunomodulatory, and anti-inflammatory properties, being perfect candidates for possible treatment of COVID-19. Further research will deliver optimized and specific therapeutic tools that will increase the preparedness of health systems for possible future epidemics.
ABSTRACT
—Coronavirus pandemic has impacted the whole education system. Suddenly, presential classrooms are replaced by online learning, leaving students and teachers to deal with various problems without any specific preparation. This research study examines the perceptions of 78 students from a Portuguese Higher Education (HE) institution towards online learning during the Coronavirus disease 19 (COVID-19) pandemic. Two months after the implementation of the online learning, they responded to a survey whose responses were analyzed by using descriptive statistics and independent Chi-squared tests. The findings of this study reveal the difficulties that the students encountered, like the lack of familiar/spatial conditions at home, the failures of Internet connection, and the fear of clarifying doubts in this context. The preference for face-to-face classes was also expressed. However, the selected platform used for the online classes, the appropriate development of the explanations and the digital contents made available by the teachers were appreciated by the students. The present research also investigates the factors that affected the study motivation of the students and the future plans regarding their studies. © 2022 by the authors.
ABSTRACT
The pandemic crisis originated by COVID-19, led some countries to implement digital tracking technologies for the protection of public health. Such practices could threaten fundamental freedoms and human rights, during and after the COVID-19 pandemic, given that the type of surveillance proposed, could pose a threat to fundamental freedoms and human rights, namely freedom, privacy and autonomy. Thus, we believe it is crucial to know some factors that promote the acceptance of such losses of freedom and privacy, respecting the autonomy of each one. This behavior incorporated in the principle of cooperation translates into a state of awareness that the behavior of each person has consequences for third parties, and, if aligned with the principles of solidarity and cooperation, it will be sufficient for people to sacrifice their fundamental rights which can be justified in a pandemic context) for the sake of the common good, which is also, and simultaneously, the good of each person.
ABSTRACT
BACKGROUND: the prevention protocols of COVID-19 impact several restrictions in the sports world, the influence of this scenario in the athletes with impairment increased associated a multifactorial condition like environment, etiology. or psychological perception. The aim of this study was to identify the influences of impairments and sports on characteristics of load training during the COVID-19 Pandemic, life satisfaction and the expectation about the influence of pandemic on the performance in the Tokyo 2020 Paralympic Games. METHODS: One hundred eighty Brazilian para-athletes, in a cross-sectional study, answered a survey about their training load before and during the Pandemic, satisfaction with life and expectation about their performance. Athletes were divided into three groups according to their sport practiced: individual sports (Ind-1);Individual sports with opposition (Ind-2) and team sports (Team). The data were analyzed by impairments and sports roups. RESULTS: Hours of training, number of sessions and rating of perceived exertion reduced during the pandemic. Limb impairment and spinal cord injurygroups reduced training hours during pandemic. Team group showed lower training sessions per week than the Ind-1 group. No difference was found in life satisfaction among the groups. Most athletes believe that the pandemic will damage their performance in the Tokyo Paralympic Games. CONCLUSIONS: Influences of COVID-19 Pandemic on training loads were identified to all groups, however there were no differences between disabilities or sports in the life satisfaction and expectation about the influence of pandemic on the performance in the Tokyo 2020 Paralympic Games.
ABSTRACT
Background: Coronavirus disease 2019 (COVID-19), had two pandemic waves in 2020, respectively in April and November. In the general population, the first wave has been characterized by a higher prevalence in Northern Italy and a higher mortality rate compared to the second one. The aim of this study was to compare the characteristics of IBD patients and negative outcomes of COVID-19 (pneumonia, hospitalization, ventilatory support, death) between the two pandemic waves in Italy. Methods: Prospective observational cohort study. Patients with diagnosis of IBD and confirmed SARS-CoV-2 infection were enrolled. Differences between first and second wave were tested for significance using the Student's t test and Fisher's test, as appropriate. A two-tailed p value <0.05 was indicative of statistical significance. Results: We enrolled 937 IBD patients from 47 participating IBD centres across Italy (219 in the first wave, 718 in the second wave). There were no significant differences between the first and the second wave in terms of age (46.3 ± 16.0 vs. 44.1 ± 15.5 years, p=0.06) and gender (female 45.7% vs. 48.2%, p= 0.54). In the first wave, a lower percentage of patients was affected by Crohn's disease (CD): 92 (42.0%) vs. 399 (55.6%) (p<0.001) while no differences were observed for disease clinical activity: 97/219 (44.3%) vs. 280/718 (38.9%) in the first and second wave, respectively (p=0.18). Regarding biologic therapy, the percentage of patients on biologics in the two waves was similar: 119/219 (54.3%) vs. 393/718 (54.7%) (p=0.94), without differences in anti-TNFalpha, anti-integrins and anti-IL12/23 distribution. During the first wave, a significantly higher percentage of patients were from Northern Italy compared to Central-Southern Italy: 171/219 (78.1%) vs. 387/718 (53.9%), respectively (p<0.001). Overall, COVID-19 negative outcomes were significantly higher in the first wave compared to the second one: 110 (50.2%) vs. 95 (13.2%), respectively (p<0.001). Also the single negative outcomes were significantly higher in the first wave: 61/219 (27.8%) vs. 84/718 (11.7%) had pneumonia, 62/219 (28.3%) vs. 76/718 (10.6%) required hospitalization, 26/219 (11.9%) vs. 39/718 (5.4%) required ventilatory support, and 12/219 (5.5%) vs. 13/718 (1.8%) died (Figure 1). Conclusion: IBD patients had higher number of COVID-19 negative outcomes in the first wave than in second wave. In the first wave, a significantly higher percentage of patients were from Northern Italy, but no significant differences in negative outcomes were observed in comparison with those from Central- Southern Italy. Overall, findings in IBD population are coherent with those observed in the general population. (Table Presented).
ABSTRACT
In recent years the quality of water and sewage treatment in Brazil is in evidence and widely discussed, due to the various cases of contamination by cyanobacteria and pathogens, giving prominence in this study: Geosmina, ZikaVirus and COVID-19, that impact water bodies. The purpose of this is to debate the current legislation and regulatory agencies that classify water quality, interpreting criteria for the preservation of aquatic life, the conservation of the areas that surround the rivers and their possible consequences for human health. The methodology was based on the literary review on national and international sites, in public bodies and institutions, the IVA – Aquatic Life Preservation Index (CETESB, 2017a/b) was defined as strategic for the preservation of the aquatic ecosystem and providing drinking water for human consumption. It was found as results: The diversity of 60 controlling agencies across the country discourage a centrality of data and control. ANA (2021) is only responsible for analyzing: pH, dissolved oxygen, conductivity and temperature, without control devices to avoid contamination, and highlighted: CEDAE in repeated episodes of geosmina contamination in the Guandu River, which prove eutrophication of this body of water and the poor quality of the water supplied to the consumer, unpleasant odor and taste. © 2021, Universidade Federal de Pernambuco. All rights reserved.
ABSTRACT
Introduction: At pediatric age, an emergency endoscopic procedure is required in a limited number of circumstances, mainly due to accidental foreign body ingestion (FBI), gastrointestinal bleeding and caustic ingestion. FBI may represent most of the procedures, occurring typically in young children (6 months to 3 years of age) at home. Although most FBIs in the gastrointestinal tract pass spontaneously without complications, endoscopic or surgical removal may be required in a few cases. SARS-CoV2 pandemic has led to significant family lifestyle changes, which forced children to stay at home for prolonged periods of time. It has been suggested that pandemic contingency may have increased the frequency of domestic accidents during lockdown period (namely FBI and caustic ingestion) and consequently the risk of potentially fatal episodes, as compared with non-pandemic periods. Aims & Methods: A retrospective analysis of the overall admissions to the pediatric emergency department of a tertiary referral hospital center with need of emergency endoscopy was performed. Children and adolescents aged between 0 and 18 years were included in the study. We compared the first 6 months of the pandemic (peak months April to September 2020-Group A) with the homologous period of the previous year (2019-Group B). The aim of the study was to evaluate if the changes in the lifestyle and hospital practices imposed by the pandemic had an impact on the frequency and profile of the emergency endoscopy. Chi-square and Mann-Whitney U tests were used for statistical analysis using IBM-SPSS®. Statistically significance was considered when p-value was under 0.05. Results: A total of 89 cases were analyzed (54% of the admissions in group A). Median age of admissions was 4.5 years. Groups did not differ for gender (p = 0.399) or age (p = 0.242). Concerning overall emergency endoscopies, 28% (25/89) occurred in children under the age of two, with most of these episodes occurring in Group A (19/89;p = 0.009). Groups did not differ considering the endoscopy indication (foreign body ingestion, caustic ingestion, food impaction and digestive hemorrhage) (p=0.899), nor about the presence of associated lesions (p = 0.597). The most frequent ingestions were caustics (18%, 16/89), coins (17%, 15/89), food impaction (12%, 11/89) and batteries (10%, 9/89). However, battery ingestions and food impactions were more frequent in 2020, respectively 67% (9/89;p = 0.419) and 64% (7/89;p = 0.49). There were no statistically significant differences on the time delay to reach the emergency department (p = 0.934) or on the time delay since emergency room admission until the endoscopic procedure (p = 0.266). More foreign bodies were removed in Group A (p = 0.026) and when lesions were present, they were more frequently seen on the esophagus (p = 0.007). Most of the patients (84%) were discharged home, after a brief recovery time after the procedure, with no difference between groups (p = 0.397). Conclusion: This study shows that there were no significant differences between both groups on the number and type of emergency endoscopies, on the time to reach the emergency room or to the performance of the endoscopy. Children under the age of 2 had more episodes with need of emergency endoscopy during the pandemic as compared to the homologous period. Overall, the pandemic did not seem to affect the quality of healthcare practice concerning emergency endoscopic procedures.
ABSTRACT
Background/objectives: Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) infection and preeclampsia may share some common pathophysiological ground, as the inflammatory changes they impose. Although the clinical course of SARS COV-2 during pregnancy is not completely understood, recent findings suggest an increased risk of preeclampsia with severe features induced by viral infection. The aim of this study is to describe the clinical course of infected pregnant women who developed preeclampsia (PE). Methods: Cohort study of SARS-COV-2 PCR positive symptomatic pregnant patients, with (n=9) and without PE (n=45), followed from admission to hospital discharge. Clinical course, delivery, neonatal and maternal outcomes were analyzed. Results: SARS-Cov-2 women with PE had higher body mass index (41,3 ± 7,8kg/m2 vs 31,6 ± 6,2kg/m2;p<0,001) and higher level of d-dimers (3,47 ± 089 vs 1,97 ± 1,18;p 0,014) than their counterpart without PE. Delivery for maternal deterioration status was also more often in PE group (23,3% vs 75%;p 0,011). No differences were observed in rates of maternal intensive care admission, need of mechanical ventilation, pulmonary image findings, maternal oxygen saturation, gestational age of delivery or neonatal outcomes. Conclusions: Development of preeclampsia in symptomatic SARS-COV-2 infected pregnant women was associated with a higher rate of maternal-indicated deliveries. No differences were found regarding neonatal or maternal clinical outcomes.
ABSTRACT
BACKGROUND AND AIMS: Italy and Lombard hospitals particularly, were hard affected by Covid-19 pandemic, mostly during spring and autumn, seasons characterized by two lockdown periods which were however, partly different as rules. During first lockdown in fact, by hospital decision, all ambulatorial activity was closed, including nephrological one. This did not happen during second lockdown period. How the different choices about hospital activity affected nephrological patients is the aim of this study. METHOD: we evaluated all nephrological advices requested by first aid units of our 3 hospitals, all located in Lombardy, to our Nephrology Unit, splitting out data in 3 periods (I lockdown, summer and II lockdown) and comparing with 2019. Data collected were: number of advices requested by day, age, sex, previous regular nephrological follow-up, Covid-19 diagnosis, nephrological diagnosis after nephrological advice and outcome. RESULTS: as shown in table 1, during I lockdown period, with hospital decision of suspending our nephrological ambulatorial activity, we suffered an incremented rate of patients approaching local first aid units compared to 2019 same period with an increased rate of acute kidney injury, mostly for dehydration, and with a higher rate of patients requiring hospitalization. All these differences resulted statistically significant vs 2019 same period (figure 1). On the other side, no statically significant difference was found during the other two examined periods, including the II lockdown, while all our ambulatories were fully operating. CONCLUSION: Covid-19 pandemic affected also the nephrological population with an increased rate of first aid units' accesses, acute kidney injury events and hospitalization comparing to 2019. However, these differences were detectable only during the I lockdown period characterized by the suspension of all ambulatorial activity, including our Unit. The absence of statistically significant differences during summer and primarily during II lockdown period demonstrates the importance of nephrological ambulatorial activity in management of renal diseases and in prevention of acute events.
ABSTRACT
Background: The COVID-19 pandemic had a high burden in Brazil. To date, data on mortality and prognostic factors of COVID-19 infection in Brazilian patients with hematological disorders are scarce. Aims: To describe the characteristics and outcomes of patients with hematological disorders admitted to the hematological COVID care unit of a reference center in Brazil;to analyze the impact of prognostic factors on in-hospital mortality. Methods: This prospective, single-center study,included 118 patients who have been admitted to the hematological COVID care unit of the Hospital das Clínicas da Faculdade de Medicina da USP, S.o Paulo, Brazil, from March to September 2020.All patients had >18 years,an underlying hematological disease and a moderate or severe COVID- 19 infection.For analyses, patients were grouped in:(1)benign or no oncological treatment(n=43),(2) intensive chemotherapy,including induction protocols for acute leukemia and stem cell transplantation conditioning(n=44) or(3) intermediate chemotherapy,including lymphoma regimens,myeloma triple treatment or continuous treatment( n=31).The primary outcome was in-hospital mortality;secondary outcome was overall survival after admission in the COVID-19 unit.Univariate analysis(UVA) used odds ratio(OR) for baseline characteristics and ROC curve analysis for laboratory tests collected at admission.Multivariate analyses(MVA) were adjusted by age and hematological disease status group.The median follow-up and survival time after COVID-19-unit admission were estimated by Kaplan- Meier method.All statistical tests were two-sided;p-values<0.05 were considered significant. Results: Median age was 58(19-90) years and 55% of patients were male. Most patients(83%)had hematological malignancies,- mainly non-Hodgkin lymphoma(29%) and multiple myeloma(19%). The most frequent benign disease was sickle cell disease(5%).12 patients had undergone hematopoietic stem cell transplantation (HSCT),4 allogeneic and 8 autologous.70% had at least one comorbidity, mostly arterial hypertension and diabetes mellitus. Thromboembolic events occurred in 9%. Median hospital stay in the COVID-19 unit was 12(1-63) days;54% needed intensive care and 41% mechanical ventilation.In-hospital mortality rate was 41%[95%CI 32-50];most deaths occurred in patients with malignancies. Median follow-up was 73(95%CI 61-81) and 54(95%CI 39-66) days after admission and discharge from the COVID-19 unit, respectively.UVA showed a risk of death increased by 25% every 10 years old.The risk of in-hospital death was 3-fold and 5-fold higher in groups 2 and 3 compared with group 1.MVA showed higher risk of death in patients from group 2(OR=11.1,95% CI 2.9- 54.8) or group 3(OR=9.7,95%CI 2.4-47.5]),who had lactate dehydrogenase( LDH)>440 U/L(OR=16.8,95%CI 4.9-71.8),C-reactive protein(CRP)>100 mg/L(OR=4.1,95%CI 1.4-13.6) or platelet count<150x10e9/L(OR=3.7,95%CI 1.3-11.7), regardless of age(OR=1.2,95%CI 1.0-1.5).79% of in-hospital deaths were from COVID-19;others were mainly due to hematological disease.The overall median survival time after admission was 92 days(95% CI 34-NA) and the 75-day survival probability was 51%(95%CI 41-60).25% of patients had hospital readmission,mostly due to other infections. Summary/Conclusion: In line with other reports,patients with hematological diseases are at higher risk of mortality from COVID-19 infection, particularly in low and middle income countries.In our cohort, prognostic factors were status of disease,platelets count,LDH and CRP. These findings might help risk stratification and prioritization of vaccines in this setting.